Background: One of the most important risks in hazardous material handling is transportation accidents that have destroyed effects on environment and safety of the road. Using risk management method could control accident causing factor.Methods: All factors that affect the environmental risks of oil products transportation was specified from storage to end of the path and weighted by analytic hierarchy Process (AHP) model. The final model was then attained using the acquired model on the basis of failure mode and effect analysis (FEMA) and the handling path was evaluated.Findings: The risk value for oil handling tankers at various areas except of two areas that located outside or within the town or with lower control of police is accessible. The reason for risk incensement in these two areas is due to existence of agriculture, residential hoses and high slope path.Conclusion: Transmission of oil storages inside and outside town and precise control of the driver ability by police is essential in reduction of environmental pollution risk of handling the oil products.

To study the energy absorption features in composite structures, it is necessary to identify the functional mechanisms and determine the impact of each on the energy absorption. In this study, the behavior of composite tubes under compressive axial load was investigated by acoustic emission monitoring. To make a filament wound composite tube, the optimal parameters were first determined using literature. In determining the optimal parameters, due to the uncertainty effect of fiber angles, from the intermediate range, the angle of 35 degrees was selected. Then, to ensure the experimental results, the finite element simulation method and the use of the VUMAT subroutine based on the 3D Hashin criterion were used. The results showed that the dominant failure mode was a local shear failure and lateral damage, which first caused the plastic deformation of the sample and then caused the growth of cracks in the fiber direction. Also, the highest percentage of failure mechanisms are matrix cracking, fiber breakage, and separation of fibers from the matrix, respectively. Finally, the use of the developed subroutine to predict the behavior of the structure was useful and was able to predict the behavior of the composite tube even after the maximum crushing force.

Acute myeloid leukemia (AML) is hematologic cancer caused by abnormal stem cell differentiation, which lead to the gathering of abnormal cells in the bone marrow. Today, with discovery and application of new drug such as monoclonal antibodies, the toxicity of chemo-therapy has been decreased. These drugs are conjugated with mAbs that enable them to target the malihnancy cells more accurately. Despite advances in the design and use of various drugs for AML treatment, leukemic cells using various mechanisms can become resistant to the cytotoxicity of drugs. Indeed, these factors result in cancer survival and treatment failure. On the other hand, predicting prognosis and relapse of the disease depends on drug resistance of leukemic cells and choosing of treatment Process. Our aim in this review article is to investigate the most common ways of AML treatment failure. By knowing these factors, more effective drugs are produced and new therapeutic protocoles are used in the treatment of AML.

This paper deals with three-dimensional evaluation of the slopes on the basis of limit analysis. An upper-bound technique of limit analysis is used in this paper to determine either the bearing capacity of a shallow foundation near a slope or the safety factor of the slope. The theorems of limit analysis (upper and lower bound) provide a powerful tool for solving problems in which limit loads need to be found. According to the upper-bound theorem, for a kinematically admissible velocity field an upper bound of the collapse load can be obtained by equating the power dissipated internally in an increment of displacement to the power expended by the external loads. Such kinematically admissible velocity fields have to comply with the kinematical boundary conditions and compatibility conditions. A rotational mechanism consisting of three slip surfaces is used to determine the factor of safety for a slope or the ultimate limit load of a foundation with eccentric load near a slope. This mechanism includes two lateral surfaces and a surface at bottom. As the soil is assumed to obey the associated flow rule, the angle between the relative velocity vector and velocity discontinuity has to be equal everywhere with soil's friction angle (j).The geometries of lateral surfaces are represented by a nonlinear differential equation. A surface with log-spiral section is used for bottom surface of the mechanism. To obtain the minimum upper-bound, an algorithm is proposed to optimize the failure mechanism. Results from this algorithm for typical conditions are comparable to those of other existing methods. Dimensionless diagrams for various conditions are presented which can be used to predict the bearing capacity of a foundation with eccentric load located on a slope.

How to profoundly change the beliefs of the polytheists during the age of revelation from the denial of the Prophet (pbuh) to the certainty of his Message and the acceptance of his full guardianship is a question worthy of attention. The order of verses about prophecy based on the order of revelation is the reason to lead a transformative Process and a special Quranic method in institutionalizing the belief of prophecy in the lives of Arabs. In the first stage, the Holy Quran in the first Makkī (Arabic: المکّیّ, suras revealed in Mecca) chapters has prepared the community from the motivational side to accept the truth of the Prophet’s (pbuh) prophecy and briefly stating the key issues surrounding it. The Holy Book of Quran at the time of the emergence of oppositions and doubts (the second stage) destroyed the arguments of the polytheists and explained the prophecy and proved its authenticity from a cognitive perspective in the second stage by presenting clear arguments. and the Holy Book of Quran in the third stage after Madanī (Arabic: المدنیّ, suras revealed in Medina) period has undertaken measures in order to fulfill the goals of the Massage by explaining the true position of the Prophet (pbuh) to deepen and operationalize the Prophetic belief through explaining practical duties for the Prophet (pbuh) and behavior based on the acceptance of Walaya (Arabic: ولایة, meaning “guardianship” or “governance”).

Many Process-aware organizations need to monitor the execution of their Business Processes (BP). Changes in BP execution can be reported as events while real-time detection of event patterns from such events can help the monitoring of model-execution conformance or business activities. Complex Event Processing (CEP) techniques can detect event patterns that are specified as CEP rules. Given the high rate of events and numerous number of complex rules, existing CEP-based solutions are not scalable. We present a novel scalable Event Driven Process Monitoring mechanism (EDBPM) using distributed CEP. Events are partitioned by Process instance identifier and the events of each partition is dispatched to a compute node. As such, the Processing load of BP monitoring is distributed adaptively to compute nodes in a load balanced manner. Using a prototyped implementation of EDBPM we show that EDBPM scales well horizontally, i. e. increases in throughput are nearly linear when the number of compute nodes increases. Compared to CPU and memory balancing in a general purpose distributed CEP-based solution, EDBPM keeps the CPU load doubly balanced and does balance the memory too, which is lacking in similar solutions

Progressive failure is developed by expanding a local initial failure from one element to another, which ultimately leads to the collapse of the whole structure or a large part of it. This phenomenon causes local damage in structural elements which can result in massive losses and significant damage. Ductility, continuity, and degree of structural expansion are among the parameters that play an important role in reducing such consequences. In this study, the behaviour of a scaled four-span steel frame, with concrete filled steel tubular columns (CFST), was evaluated under progressive failure by removing the middle column. This work was done using the finite element method in ABAQUS. This work was carried out by examining the effect of reinforced triangular plate, haunch and angle steel reinforcements, reduced section in flange and web as well as posttensioned FRP cables along with sensitivity analysis. The findings indicated that among the proposed anti-collapse methods, the maximum yield strength, the maximum ultimate strength and ductility ratio belong to angle steel reinforcement with 140. 24 KN, reinforced triangular plate with 259. 6 KN and RBS with 21. 16 method. However, in a comprehensive comparison, the method of adding reinforced triangular plate was the best anti-collapse method since it avoids damage to the columns. Additionally, the change in compressive and tensile strength of the concrete did not have much effect on the frame behaviour in the progressive failure. Moreover, the frame with non-concrete columns has a ductility ratio 3 times higher than SRCT case, although the frame with SRCT columns has a 14 percent higher yield strength.

Increasing water in the slope layers induced the failure of slopes. . Water is the most important factor in most of the slope stability analysis. Although water does not directly lead to the slopes displacement, but is an important factor for the following reasons: (1) water increases due to rainfall and snow melt will lead to increasingslope weight. (2) Water can change the angle of slope (angle of slope is an angle that slope is stable in this angle). (3) Water can be absorbed or excreted by minerals are available in the soil. After adding the water, the weight of the rock and soil increases. (4) Water can dissolve the cement between the seeds and cohesion between the seeds is lost. In this paper, the feasibility of using piles to stabilize layered earth slopes were studied. A set of physical modeling of foundations was performed adjacent to layered slopes. The deformation pattern and shear strains of soil near slope and below surcharge load were studied. For this purpose, a comprehensive set of tests and numerical analysis were undertaken on different slope models. In each step of loading, digital image of deformed soil was captured and image Processing was applied with GeoPIV software for investigation of soil deformation on slope and below the footing. the effect of pile and saturated conditions effects on improvement ratio (safety factor of stabilized slope with pile / safety factor of the slope stability without piles), bearing capacity of foundations, slope stability and slip surface shape in layered slope were investigated. The results show that the slip surface of layered slopes differs depending strongly on the installed pile positions and layered saturation conditions. In consideration of the model tests and numerical analysis results, it is found that, when clayey layer was near ground surface, changes in clayey layers water content significantly affected on slip surface and layered slope stability. Consideration of slipe surface shape for different layers saturation canditions, it is found, saturation of below layers which is located below the slip surface, has not significant effects on slope stability and slip surface shape. But with increasing upper layers water content, large volume of soil were failed. Experimental and numerical results show, for stable slope before applied surcharge load or before water content increases, critical slipe surface occurred in front the installed pile. But for unstable slope, critical slip surface positions depend on layers saturation and soil properties and occurred in front or behind or in upper and lower part of pile. In general The critical slip surface location dependent on water table level conditions and location of pile. Also from the experimental and numerical results it is found, the optimum location of pile for increasing bearing capacity of foundation which is located on slope crest, is near slope crest and maximum magnitude of Bearing capacity ratio ((bearing capacity of reinforced slope/ bearing capacity of non-reinforced slope)(BCR)) was obtained when piles installed near slope crest. Also optimum location of pile for increasing slope stability are found near mid of slope. A close agreement between the experimental and numerical results in failure mechanism and the critical values of the studied parameters is observed.